![]() Gunter Kuhnle, a professor of nutrition and food science at the University of Reading, pointed to some details in the study that may have skewed the results. When essential fatty acids decrease and free fatty acids increase, this may raise anxiety and depression, the researchers found. Long-term exposure to acrylamide can also cause disruptions to the brain’s lipid metabolism. All of these effects may contribute to anxiety and depression, the researchers surmised. Previous studies have linked such disruptions to inflammation and oxidative stress. Decreased permeability interrupted delivery of nutrients and oxygen to the brain. Ketamine Assisted Psychotherapy for Treatment-Resistant DepressionĪcrylamides significantly down-regulated the gene expression of tjp2a related to brain-blood barrier permeability, the study suggested. The authors pointed to an investigation of long-term exposure to acrylamides causing anxiety- and depressive-like behaviors in adult zebrafish. Previous studies have blamed acrylamides for several adverse health effects, including neurotoxicity, carcinogenicity, and reproductive toxicity. A chemical process known as the Maillard reaction produces acrylamide as a byproduct. Cooking starchy foods such as potatoes at high temperatures forms acrylamides. Acrylamide-Brain ConnectionĪ class of chemicals called acrylamides appears to be the culprit. Subjects who frequently ate fried foods, especially fried potatoes, had a 12 percent higher risk of anxiety and a 7 percent higher risk of depression. The PNAS research followed 140,728 UK Biobank participants over a ten year period. Frequent consumption of fried foods, especially deep fried potatoes, was associated with a higher risk of anxiety and depression in a new study conducted by researchers from Hangzhou, China. ![]() The next time you want fries with that, you might want to reconsider. Some scientists expressed skepticism over the findings, saying a host of other dietary and lifestyle factors may be contributing factors.A class of chemicals produced in frying known as acrylamides may cause inflammation and oxidative stress in a variety of ways that trigger depression and anxiety in the brain.A new study found that eating a lot of French fries is linked to a 12 percent higher risk of depression and 7 percent higher risk of anxiety.Clinical Relevance: French Fries may increase the risk of depression and anxiety
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